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SCN1A Antibody / Nav1.1 (Center Region)

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na (+) ions may pass in accordance with their electrochemical gradient.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000-1:2000, FACS: 1:25

UniProt

P35498

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids from human SCN1A was used as the immunogen for the SCN1A antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, FACS

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the SCN1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This SCN1A antibody is available for research use only.

Storage Conditions

Aliquot the SCN1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the SCN1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse, Rat

Image Legend

Western blot testing of human U-87 MG cell lysate with SCN1A antibody at 1:2000. Predicted molecular weight ~229 kDa, routinely observed at ~250 kDa.

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