MKS1 Antibody / Meckel syndrome type 1 protein (N-Terminal Region)
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:2000
UniProt
Q9NXB0
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 90-124 from human MKS1 was used as the immunogen for the MKS1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MKS1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MKS1 antibody is available for research use only.
Storage Conditions
Aliquot the MKS1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of human 1) kidney and 2) lung tissue lysate with MKS1 antibody at 1:2000. Predicted molecular weight ~65 kDa.
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