Folate Receptor beta Antibody / FOLR2
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:2000
UniProt
P14207
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human FOLR2 protein was used as the immunogen for the Folate Receptor beta antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
1905CT501.41.76
Applications
WB
Purity
Protein G purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Folate Receptor beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Folate Receptor beta antibody is available for research use only.
Storage Conditions
Aliquot the Folate Receptor beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of human 1) spleen and 2) placenta lysate with Folate Receptor beta antibody at 1:1000. Predicted molecular weight ~29 kDa.
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