DNAJC3 Antibody (Center Region)
DnaJ homolog subfamily C member 3 is involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:2000
UniProt
Q13217
Host
Rabbit
Reactivity
Mouse
Immunogen
A portion of amino acids 189-223 from human DNAJC3 was used as the immunogen for the DNAJC3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the DNAJC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DNAJC3 antibody is available for research use only.
Storage Conditions
Aliquot the DNAJC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Prediction Reactivity
Human, Rat
Image Legend
Western blot testing of mouse NIH3T3 cell lysate with DNAJC3 antibody at 1:2000. Predicted molecular weight ~58 kDa.
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