HtrA2 Antibody
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500, Immunoprecipitation: suitable
UniProt
O43464
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant protein was used as the immunogen for this HtrA2 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
8G11-4B8-4F10-G5
Applications
WB, IP
Purity
Protein G affinity
Format
Purified
Buffer
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Reconstitution
Store the HtrA2 antibody at -20oC.
Limitations
This HtrA2 antibody is available for research use only.
Storage Conditions
Store the HtrA2 antibody at -20°C.
Formulation
In PBS with 50% glycerol and 0.03% ProClin 300
Applications Notes
Image Legend
Western blot testing of human 293T cell lysate with HtrA2 antibody at 1:500. Predicted molecular weight: 38-49 kDa.
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