HtrA2 Antibody
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O43464
Host
Mouse
Reactivity
Mouse, Hamster
Immunogen
A human recombinant protein was used as the immunogen for this HtrA2 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
1H8-C12-F8
Applications
WB
Purity
Protein G affinity
Format
Purified
Buffer
Antibody in PBS with 50% Glycerol and 0.02% sodium azide
Reconstitution
Store the HtrA2 antibody at -20oC.
Limitations
This HtrA antibody is available for research use only.
Storage Conditions
Store the HtrA2 antibody at -20°C.
Formulation
In PBS with 50% glycerol and 0.02% sodium azide
Applications Notes
Prediction Reactivity
Human
Image Legend
Western blot testing of hamster CHO-K1, mouse MEF and mouse NIH3T3 cell lysates using HtrA2 antibody at 1:1000. Predicted molecular weight: 38-49 kDa.
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