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P38 MAPK Antibody / MAPK14

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500

UniProt

Q16539

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

A human recombinant partial protein was used as the immunogen for this MAPK14 / p38 MAPK antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

5A1-C5-F11

Applications

WB

Purity

Protein G affinity

Format

Purified

Buffer

Antibody in PBS with 50% Glycerol and 0.03% ProClin 300

Reconstitution

Store the p38 MAPK antibody at -20oC.

Limitations

This p38 MAPK antibody is available for research use only.

Storage Conditions

Store the p38 MAPK antibody at -20°C.

Formulation

In PBS with 50% glycerol and 0.03% ProClin 300

Applications Notes

The stated application concentrations are suggested starting points. Titration of the p38 MAPK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of mouse C2C12, rat PC12, human HepG2, monkey COS7, rat C6, mouse NIH3T3 and human HeLa cell lysates with p38 MAPK antibody at 1:500. Predicted molecular weight: 38-41 kDa.

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