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TLR7 Antibody

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

Q9NYK1

Host

Mouse

Reactivity

Human

Immunogen

A human recombinant partial protein was used as the immunogen for this TLR7 antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

3F11-2C9-D8

Applications

WB

Purity

Protein G affinity

Format

Purified

Buffer

Antibody in PBS with 50% Glycerol and 0.03% ProClin 300

Reconstitution

Store the TLR7 antibody at -20oC.

Limitations

This TLR7 antibody is available for research use only.

Storage Conditions

Store the TLR7 antibody at -20°C.

Formulation

In PBS with 50% glycerol and 0.03% ProClin 300

Applications Notes

The stated application concentrations are suggested starting points. Titration of the TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of A) CHO-K1 cells transfected with a partial TLR7 protein and B) untransfected CHO-K1 cell lysate using TLR7 antibody at 1:2000. Expected size of the partial protein ~40 kDa.

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