FADD Antibody
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500, Immunoprecipitation: suitable
UniProt
Q13158
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant protein was used as the immunogen for this FADD antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
5E8-A7
Applications
WB, IP
Purity
Protein G affinity
Format
Purified
Buffer
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Reconstitution
Store the FADD antibody at -20oC.
Limitations
This FADD antibody is available for research use only.
Storage Conditions
Store the FADD antibody at -20°C.
Formulation
In PBS with 50% glycerol and 0.03% ProClin 300
Applications Notes
Image Legend
Western blot testing of SW480, Jurkat and HeLa cell lysates using FADD antibody at 1:500. Predicted molecular weight ~28 kDa.
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