IL-23 Antibody (p19/alpha subunit)
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
Q9NPF7
Host
Rabbit
Reactivity
Mouse
Immunogen
Amino acids 33-67 from the human protein were used as the immunogen for this IL-23 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Antibody in 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IL-23 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IL-23 antibody is available for research use only.
Storage Conditions
Aliquot the IL-23 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Prediction Reactivity
Human
Image Legend
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