PKD2 Antibody / Protein kinase D2
Protein kinase D2 is a serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress- induced NF-kappa-B activation, inhibition of HDAC7 transcriptional repression, signaling downstream of T-cell antigen receptor (TCR) and cytokine production, and plays a role in Golgi membrane trafficking, angiogenesis, secretory granule release and cell adhesion.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-2000
UniProt
Q9BZL6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 556-590 from the human protein was used as the immunogen for the PKD2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PKD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PKD2 antibody is available for research use only.
Storage Conditions
Aliquot the PKD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PKD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Rat
Image Legend
Western blot testing of 1) human brain lysate and 2) mouse NIH3T3 cell lysate with PKD2 antibody at 1:2000. Predicted molecular weight: 97 kDa.
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