Kindlin-3 Antibody / FERMT3
Fermitin family homolog 3, also called Kindlin-3, plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) . Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity) .
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000
UniProt
Q86UX7
Host
Rabbit
Reactivity
Mouse
Immunogen
A portion of amino acids 117-151 from the mouse protein was used as the immunogen for the Kindlin-3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Kindlin-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Kindlin-3 antibody is available for research use only.
Storage Conditions
Aliquot the Kindlin-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Kindlin-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Human
Image Legend
Western blot testing of mouse spleen lysate with Kindlin-3 antibody at 1:2000. Predicted molecular weight: 76 kDa.
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