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PRDM16 Antibody

PR domain zinc finger protein 16 binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

Product Specifications

UniProt

Q9HAZ2

Host

Mouse

Immunogen

A partial recombinant protein corresponding to amino acids 779-996 from the human protein was used as the immunogen for the PRDM16 antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Applications

WB

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PRDM16 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PRDM16 antibody is available for research use only.

CAS Number

9007-83-4

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