AKAP13 Antibody
A-kinase anchor protein 13 anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element- specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:4000-8000
UniProt
Q12802
Host
Mouse
Reactivity
Human
Immunogen
A partial recombinant protein corresponding to amino acids 18-170 from the human protein was used as the immunogen for the AKAP13 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
1742CT411.87.24
Applications
WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the AKAP13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This AKAP13 antibody is available for research use only.
Storage Conditions
Aliquot the AKAP13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the AKAP13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of recombinant protein with AKAP13 antibody at 1:8000.
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