CTCF Antibody
CCCTC-binding factor is a chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000-4000
UniProt
P49711
Host
Mouse
Reactivity
Human, Rat
Immunogen
A partial recombinant protein corresponding to amino acids 445-727 from the human protein was used as the immunogen for the CTCF antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
1723CT382.14.9
Applications
WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CTCF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CTCF antibody is available for research use only.
Storage Conditions
Aliquot the CTCF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CTCF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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