SULF1 Antibody / Sulfatase 1
Sulfatase 1 exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000, Flow cytometry: 1:25/million cells
UniProt
Q8IWU6
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 704-738 from the human protein was used as the immunogen for the SULF1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SULF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SULF1 antibody is available for research use only.
Storage Conditions
Aliquot the SULF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SULF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human skeletal muscle lysate with SULF1 antibody at 1:2000. Predicted molecular weight: 101 kDa.
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