MGAT4B Antibody

Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosynthesis.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000-2000

UniProt

Q9UQ53

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 32-62 from the human protein was used as the immunogen for the MGAT4B antibody.

Clonality

Polyclonal

Isotype

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MGAT4B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MGAT4B antibody is available for research use only.

Storage Conditions

Aliquot the MGAT4B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the MGAT4B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human pancreas lysate with MGAT4B antibody at 1:2000. Predicted molecular weight ~63 kDa but may be observed at higher molecular weights due to glycosylation.