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LLGL2 Antibody / HGL

The lethal (2) giant larvae protein of Drosophila / Human giant larvae homolog plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1000

UniProt

Q6P1M3

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 940-973 from the human protein was used as the immunogen for the LLGL2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

SAS precipitation followed by dialysis in PBS

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the LLGL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This LLGL2 antibody is available for research use only.

Storage Conditions

Aliquot the LLGL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the LLGL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of LLGL2 antibody and K562 cell lysate. Predicted molecular weight ~113 kDa.

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