ARD1A Antibody / NAA10
N-alpha-acetyltransferase 10 is the catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development.
Product Specifications
UniProt
P41227
Host
Rabbit
Immunogen
A portion of amino acids 135-167 from the human protein was used as the immunogen for the NAA10 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the NAA10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NAA10 antibody is available for research use only.
CAS Number
9007-83-4
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