ARD1A Antibody / NAA10

N-alpha-acetyltransferase 10 is the catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000-2000

UniProt

P41227

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 135-167 from the human protein was used as the immunogen for the NAA10 antibody.

Clonality

Polyclonal

Isotype

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the NAA10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NAA10 antibody is available for research use only.

Storage Conditions

Aliquot the NAA10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the NAA10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse, Bovine

Image Legend

Western blot testing of human 1) SK-BR-3, 2) HeLa, 3) HCT116, 4) MCF-7 and 5) HL-60 cell lysate with NAA10 antibody at 1:2000. Predicted molecular weight: 26 kDa.