MEAF6 Antibody
MYST/Esa1-associated factor 6 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000
Gene ID
64769
UniProt
Q9HAF1
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 120-154 from the human protein was used as the immunogen for the MEAF6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MEAF6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MEAF6 antibody is available for research use only.
Storage Conditions
Aliquot the MEAF6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the MEAF6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Mouse
Image Legend
Western blot testing of human PC-3 cell lysate with MEAF6 antibody at 1:2000. Predicted molecular weight: 22 kDa.
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