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LASS4 Antibody / CerS4

LAG1 longevity assurance homolog 4 (LASS4), also called Ceramide synthase 4 (CerS4) may be either a bona fide (dihydro) ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000-2000, FACS (Intracellular) : 1:25

UniProt

Q9HA82

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 21-51 from the human protein was used as the immunogen for the LASS4 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, FACS

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the LASS4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This LASS4 antibody is available for research use only.

Storage Conditions

Aliquot the LASS4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the LASS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human 1) HeLa, 2) HT-1080, 3) Jurkat, 4) LNCaP and 5) PC-3 cell lysate with LASS4 antibody at 1:2000. Predicted molecular weight: 46 kDa.

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