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PF4 Antibody / Platelet factor 4

Platelet factor 4 is released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000-2000

UniProt

P02776

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 28-59 from the human protein was used as the immunogen for the PF4 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PF4 antibody is available for research use only.

Storage Conditions

Aliquot the PF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the PF4 antibody may be required due to differences in protocols and substrate sensitivity.

Image Legend

Western blot testing of human spleen lysate with PF4 antibody at 1:2000. Expected molecular weight: ~8/16/32 kDa (monomer/dimer/tetramer) .

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