INTS6 Antibody
Integrator complex subunit 6 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000
Gene ID
26512
UniProt
Q9UL03
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 135-167 from the human protein was used as the immunogen for the INTS6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the INTS6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This INTS6 antibody is available for research use only.
Storage Conditions
Aliquot the INTS6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the INTS6 antibody may be required due to differences in protocols and substrate sensitivity.
Prediction Reactivity
Mouse
Image Legend
Western blot testing of human 1) A431 and 2) HeLa cell lysate with INTS6 antibody at 1:2000. Predicted molecular weight: 100 kDa.
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