IGF2R Antibody
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000
Gene ID
3482
UniProt
P11717
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 2424-2458 from the human protein was used as the immunogen for the IGF2R antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IGF2R antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IGF2R antibody is available for research use only.
Storage Conditions
Aliquot the IGF2R antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IGF2R antibody may be required due to differences in protocols and substrate sensitivity.
Image Legend
Western blot testing of human 1) 293T/17, 2) HeLa and 3) Jurkat cell lysate with IGF2R antibody at 1:2000. Predicted molecular weight: 274 kDa.
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