PDS5B Antibody / AS3

Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000-2000

UniProt

Q9NTI5

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 1197-1228 from the human protein was used as the immunogen for the PDS5B antibody.

Clonality

Polyclonal

Isotype

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PDS5B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PDS5B antibody is available for research use only.

Storage Conditions

Aliquot the PDS5B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the PDS5B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human 1) 293T/17, 2) DU-145, 3) LNCaP, 4) Raji, 5) U-2OS and 6) HeLa cell lysate with PDS5B antibody at 1:2000. Predicted molecular weight: 165 kDa.