Atrogin 1 Antibody / FBXO32
F-box only protein 32 / Atrogin 1 is a substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000
UniProt
Q969P5
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 17-49 from the human protein was used as the immunogen for the Atrogin 1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Atrogin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Atrogin 1 antibody is available for research use only.
Storage Conditions
Aliquot the Atrogin 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Atrogin 1 antibody may be required due to differences in protocols and substrate sensitivity.
Prediction Reactivity
Bovine, Mouse, Pig, Rat
Image Legend
Western blot testing of human 1) HeLa and 2) Jurkat cell lysate with Atrogin 1 antibody at 1:2000. Predicted molecular weight: 42 kDa.
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