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DEDD2 Antibody

DNA-binding death effector domain-containing protein 2 may play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1000

UniProt

Q8WXF8

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 43-75 from the human protein was used as the immunogen for the DEDD2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the DEDD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This DEDD2 antibody is available for research use only.

Storage Conditions

Aliquot the DEDD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the DEDD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse

Image Legend

Western blot testing of human SW480 cell lysate with DEDD2 antibody at 1:1000. Predicted molecular weight: 36 kDa.

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