NAT8L Antibody / N-acetyltransferase 8-like protein

N-acetyltransferase 8-like protein plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, Immunohistochemistry (FFPE) : 1:250

UniProt

Q8N9F0

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 59-93 from the human protein was used as the immunogen for the NAT8L antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the NAT8L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NAT8L antibody is available for research use only.

Storage Conditions

Aliquot the NAT8L antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the NAT8L antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse

Image Legend

IHC staining of FFPE human kidney tissue with NAT8L antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.