E-Cadherin Antibody / CDH1
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. E-Cadherin/CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000-4000, IHC (FFPE) : 1:25
UniProt
P12830
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant protein of amino acids 1-392 was used as the immunogen for the E-Cadherin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
1579CT577.150.80
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the E-Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This E-Cadherin antibody is available for research use only.
Storage Conditions
Aliquot the E-Cadherin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the E-Cadherin antibody may be required due to differences in protocols and substrate sensitivity.
Location
Cytoplasmic, membranous
Image Legend
Frequently Asked Questions
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