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TIGIT Antibody / VSTM3 / VSIG9

TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000

UniProt

Q495A1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 12-142 from the human protein was used as the immunogen for this TIGIT antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the TIGIT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This TIGIT antibody is available for research use only.

Storage Conditions

Aliquot the TIGIT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the TIGIT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of 1) mouse EL4, human 2) fetal thymus, 3) spleen, 4) HUT78, 5) Jurkat and 6) Molt-4 lysate with TIGIT antibody. Predicted molecular weight ~26 kDa.

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