Nestin Antibody
Nestin is a class VI intermediate filament protein expressed predominantly in stem cells of the neural tube but absent from virtually all differentiated CNS cells. In the CNS, nestin is downregulated upon differentiation and replaced by neurofilaments. Transient expression of nestin has been postulated as a key step committing cells to the neural differentiation pathway. Nestin expression has also been observed in pancreatic hematopoietic stem cell populations.
Product Specifications
UniProt
P48681
Host
Rabbit
Immunogen
A portion of amino acids 1560-1590 from the human protein was used as the immunogen for this Nestin antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, IF, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Nestin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Nestin antibody is available for research use only.
CAS Number
9007-83-4
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