GAB1 Antibody

GRB2-associated-binding protein 1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

Q13480

Host

Mouse

Reactivity

Human

Immunogen

This GAB1 antibody was produced from mice immunized with a GST fusion protein encoding full length human GAB1.

Clonality

Monoclonal

Isotype

IgG1

Clone

1AT1979

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Gab1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This GAB1 antibody is available for research use only.

Storage Conditions

Aliquot the GAB1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the GAB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of GAB1 antibody: Wild-type (+/+) and GAB1-/- (-/-) cells were heat shocked (HS) at 42oC for 1 h or irradiated with UV-B light (400 J/m2) and then incubated at 37oC for 1 h. IP was done with an anti-JNK2 Ab and immunoprecipitates tested with GAB1 antibody.