LEF1 Antibody
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:8000
UniProt
Q9UJU2
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 10-37 from the human protein was used as the immunogen for this LEF1 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
661CT8.3.5
Applications
WB, ELISA
Purity
Ascites
Format
Ascites
Buffer
In ascites with 0.09% sodium azide
Reconstitution
Aliquot the LEF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This LEF1 antibody is available for research use only.
Storage Conditions
Aliquot the LEF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In ascites with 0.09% sodium azide
Applications Notes
Titration of the LEF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Rat
Image Legend
LEF1 antibody western blot analysis in K562 lysate. Predicted molecular weight ~44 kDa but commonly observed at 35-55 kDa.
Frequently Asked Questions
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