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ABO Antibody

This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:200-1:6400

UniProt

P16442

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 41-68 from the human protein was used as the immunogen for this ABO antibody.

Clonality

Monoclonal

Isotype

IgM

Clone

593CT3.2.2

Applications

WB, ELISA

Purity

Ascites

Format

Ascites

Buffer

In ascites with 0.09% sodium azide

Reconstitution

Aliquot the ABO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ABO antibody is available for research use only.

Storage Conditions

Aliquot the ABO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In ascites with 0.09% sodium azide

Applications Notes

Titration of the ABO antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

ABO antibody western blot analysis in K562 lysate

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