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IL-2 Antibody

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7) . The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:100-1:1600

UniProt

P60568

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 50-77 from the human protein was used as the immunogen for this IL-2 antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

627CT14.8.1

Applications

WB, ELISA

Purity

Ascites

Format

Ascites

Buffer

In ascites with 0.09% sodium azide

Reconstitution

Aliquot the IL-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This IL-2 antibody is available for research use only.

Storage Conditions

Aliquot the IL-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In ascites with 0.09% sodium azide

Applications Notes

Titration of the IL-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IL-2 antibody western blot analysis in K562 lysate. Predicted molecular weight ~17 kDa

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