CD30 Antibody
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:100-1:1000
UniProt
P28908
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 294-321 from the human protein was used as the immunogen for this CD30 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
595CT15.5.1
Applications
WB, ELISA
Purity
Ascites
Format
Ascites
Buffer
In ascites with 0.09% sodium azide
Reconstitution
Aliquot the CD30 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD30 antibody is available for research use only.
Storage Conditions
Aliquot the CD30 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In ascites with 0.09% sodium azide
Applications Notes
Titration of the CD30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
CD30 antibody western blot analysis in K562 lysate. Predicted molecular weight: 53-120 kDa depending on glycosylation level.
Documents
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