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CD30 Antibody

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:100-1:1000

UniProt

P28908

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 294-321 from the human protein was used as the immunogen for this CD30 antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

595CT15.5.1

Applications

WB, ELISA

Purity

Ascites

Format

Ascites

Buffer

In ascites with 0.09% sodium azide

Reconstitution

Aliquot the CD30 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CD30 antibody is available for research use only.

Storage Conditions

Aliquot the CD30 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In ascites with 0.09% sodium azide

Applications Notes

Titration of the CD30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

CD30 antibody western blot analysis in K562 lysate. Predicted molecular weight: 53-120 kDa depending on glycosylation level.

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