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IGF2 Antibody

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:8000

UniProt

P01344

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 39-68 from the human protein was used as the immunogen for this IGF2 antibody.

Clonality

Monoclonal

Isotype

IgM

Clone

519CT14.3.6

Applications

WB, ELISA

Purity

Ascites

Format

Ascites

Buffer

In ascites with 0.09% sodium azide

Reconstitution

Aliquot the IGF2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This IGF2 antibody is available for research use only.

Storage Conditions

Aliquot the IGF2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In ascites with 0.09% sodium azide

Applications Notes

Titration of the IGF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IGF2 antibody western blot analysis in A549 lysate. Predicted molecular weight: 20, 20, 26 kDa (isoforms 1-3) .

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