CD10 Antibody / Neprilysin
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:4000
UniProt
P08473
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 272-300 from the human protein was used as the immunogen for this CD10 antibody.
Clonality
Monoclonal
Isotype
IgM
Clone
307CT12.12.5
Applications
WB, ELISA
Purity
Ascites
Format
Ascites
Buffer
In ascites with 0.09% sodium azide
Reconstitution
Aliquot the CD10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD10 antibody is available for research use only.
Storage Conditions
Aliquot the CD10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In ascites with 0.09% sodium azide
Applications Notes
Titration of the CD10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cell surface, Cytoplasmic
Image Legend
CD10 antibody western blot analysis in CEM lysate.
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