P16INK4a Antibody
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
P42771
Host
Rabbit
Reactivity
Human
Immunogen
This p16INK4a antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 145-176 amino acids from human p16-INK4a.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the p16INK4A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This p16INK4a antibody is available for research use only.
Storage Conditions
Aliquot the p16INK4a antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the p16INK4a antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of p16INK4a antibody at 1:2000 dilution + HeLa lysate; Predicted molecular weight: 17 kDa.
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