NOTCH4 Antibody
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity) .
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
Q99466
Host
Rabbit
Reactivity
Human
Immunogen
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the NOTCH4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NOTCH4 antibody is available for research use only.
Storage Conditions
Aliquot the NOTCH4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the NOTCH4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of NOTCH4 antibody at 1:2000 dilution + human liver lysate; Predicted band size : 210 kDa.
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