VANGL2 Antibody
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity) .
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
Q9ULK5
Host
Rabbit
Reactivity
Human
Immunogen
This VANGL2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-410 amino acids from human VANGL2.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the VANGL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This VANGL2 antibody is available for research use only.
Storage Conditions
Aliquot the VANGL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the VANGL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of VANGL2 antibody at 1:2000 dilution + DU145 lysate; Predicted molecular weight ~60 kDa.
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