Caspase-4 Antibody (large subunit)

Involved in the activation cascade of caspases responsible for apoptosis execution. Involved in ER-stress induced apoptosis. Cleaves caspase-1.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000

UniProt

P49662

Host

Rabbit

Reactivity

Human

Immunogen

This Caspase-4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 163-197 amino acids from the central region of human CASP4.

Clonality

Polyclonal

Isotype

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the Caspase-4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Caspase-4 antibody is available for research use only.

Storage Conditions

Aliquot the Caspase-4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Caspase-4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of Caspase-4 antibody at 1:2000 dilution + human Raji lysate; Expected molecular weight ~43 kDa (precursor), ~30 kDa (pro + large subunit), ~20 kDa (large subunit) .