Notch1 Antibody

Notch1 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. It is involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000

UniProt

Q01705

Host

Rabbit

Reactivity

Mouse

Immunogen

This Notch1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 2403-2437 amino acids from the C-terminal region of mouse Notch1.

Clonality

Polyclonal

Isotype

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Notch1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Notch1 antibody is available for research use only.

Storage Conditions

Aliquot the Notch1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Notch1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of Notch1 antibody at 1:2000 dilution + mouse lung lysate; Predicted molecular weight: ~ 270 kDa (full length), ~ 120 kDa (transmembrane fragment) .