DRP1 Antibody / Dynamin-related protein 1 / DNM1L
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O00429
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the DRP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DRP1 antibody is available for research use only.
Storage Conditions
Aliquot the DRP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the DRP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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