EED Antibody

Polycomb protein EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin β7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [Wiki]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

O75530

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This EED antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 38-72 amino acids from the N-terminal region of human EED.

Clonality

Polyclonal

Isotype

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the EED antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This EED antibody is available for research use only.

Storage Conditions

Aliquot the EED antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the EED antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of EED antibody at 1:1000 dilution + mouse brain lysate; Predicted molecular weight: 50 kDa (isoform 1), 53 kDa (isoform 2), 46 kDa (isoform 3) .