KDM6B Antibody
Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
O15054
Host
Rabbit
Reactivity
Mouse
Immunogen
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the KDM6B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This KDM6B antibody is available for research use only.
Storage Conditions
Aliquot the KDM6B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the KDM6B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of KDM6B antibody at 1:2000 dilution + mouse lung lysate; Predicted molecular weight ~176 kDa.
Documents
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