Suz12 Antibody
Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity) . Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q80U70
Host
Rabbit
Reactivity
Mouse
Immunogen
This Suz12 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 496-530 amino acids from the mouse protein.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Suz12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Suz12 antibody is available for research use only.
Storage Conditions
Aliquot the Suz12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Suz12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Human
Image Legend
Frequently Asked Questions
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