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Pax6 Antibody

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P63015

Host

Rabbit

Reactivity

Mouse

Immunogen

This mouse Pax6 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 404-436 amino acids from the C-terminal region of mouse Pax6.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Pax6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Pax6 antibody is available for research use only.

Storage Conditions

Aliquot the Pax6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Pax6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Human, Rat, Bovine, Chicken, Zebrafish, Xenopus

Image Legend

Western blot analysis of lysate from mouse cerebellum tissue lysate using Pax6 antibody; Ab was diluted at 1:1000. Predicted molecular weight ~48kDa.

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