SOX7 Antibody
Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity) . May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity) . Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity) . Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9BT81
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 224-258 of the human protein was used as the immunogen for the SOX7 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SOX7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SOX7 antibody is available for research use only.
Storage Conditions
Aliquot the SOX7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Frequently Asked Questions
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