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Wdr5 Antibody

Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P61965

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This mouse Wdr5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the region of mouse Wdr5.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Wdr5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Wdr5 antibody is available for research use only.

Storage Conditions

Aliquot the Wdr5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Wdr5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Rat

Image Legend

Western blot analysis of lysate from 1) human liver tissue and 2) mouse NIH3T3 cell line using Wdr5 antibody at 1:1000. Predicted molecular weight ~36 kDa.

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